Developing cancer therapies for patients in need of new options

Australis brings you AUS_001

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Let’s create a world where fewer children and adults suffer.

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Australis Cancer Therapy

Found in Nature. Backed by Science.

Australis Cancer Therapy

Encouraging pre-clinical efficacy and safety data.

Australis Cancer Therapy

Global clinical development strategy.

Australis Cancer Therapy

Developing an oral formulation to potentially allow for patient dosing at home.

Who is Australis?

Australis is a global biopharmaceutical company deeply driven to bring new therapies to cancer patients in need. Our in-house research is centerd around our laboratory in Simi Valley, California, by a team of dedicated PhD scientists.

Our third-party research is performed and reviewed by esteemed professionals worldwide.

Australis-print

Why AUS_001?

Australis Cancer Therapy

Vetted by scientists and doctors

We have partnered with esteemed professionals worldwide to review and perform research.

Australis Cancer Therapy

Proven to target hard-to-treat cancers

AUS_001 shows strong pre-clinical efficacy against a wide range of cancers, including those typically resistant to traditional treatments. In vitro data reveals that AUS_001 has effectively targeted 24 types of cancer.

Australis Cancer Therapy

Pre-Clinical safety data

On average 20x more of AUS_001 is needed to inhibit the growth of healthy vs. neoplastic cells, indicating an encouraging safety margin.

Home beekeeper

Global partners

Australis-partners

Our story, our nature

An abundance of vitro and in vivo studies unveiled encouraging efficacy in many types of cancers and we are preparing to enter clinical trials.

Nature's gift

Kangaroo Island’s unique biodiversity hosts a special type of ground-foraging bee, unique to Kangaroo Island. By studying the island’s bees, Australis scientists discovered a resin in local grass that was only produced to defend against kangaroos. The bees harvested the resin to make propolis to disinfect their hives. That propolis contained what is now AUS_001.

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0%

Of all medicines were discovered in plant species.

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0%

Of earth’s plants have been studied for treatments.

Data from our tests

AUS_001 has demonstrated very encouraging preclinical data.
These are our results so far:

In Vitro

High potency against 24 types of cancer.

In Vivo

Strong efficacy against seven cancers to date, with encouraging safety data, including:

Breast cancer

Pancreatic cancer

Bladder cancer

Melanoma

Kidney cancer

Lung cancer

Glioblastoma

Australis-scientist
"

We’ve been looking 40 years for a drug like this to replace the Taxol family.

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- Leading researcher at the National Cancer Institute

Our timeline

We’ve come a long way since that day on Kangaroo Island back in the 2000s.
With your help, we can make even greater progress to get AUS_001 into the hands of those who need it.

2019-01-01

2009

Australis Cancer Therapy

Compound isolated from propolis.
2019-01-01

2019-01-01

2011

Australis Cancer Therapy

Cancer breakthrough with first patent filed.
2019-01-01

2019-01-01

2012

Australis Cancer Therapy

In vitro proof of concept.
2019-01-01

2019-01-01

2015

Australis Cancer Therapy

In vivo efficacy confirmed.
2019-01-01

2019-01-01

2019

Australis Cancer Therapy

Oral formulation and brain penetration proven.
2019-01-01

2019-01-01

2020

Australis Cancer Therapy

Additional in vivo data, including tumour eradication.
2019-01-01

2019-01-01

2021

Australis Cancer Therapy

Continued efficacy data.
2019-01-01

2019-01-01

2022

Australis Cancer Therapy

Mechanism of action characterised.
2019-01-01

2019-01-01

2023

Australis Cancer Therapy

PK/ADME data generated.
2019-01-01

2019-01-01

2024

Australis Cancer Therapy

First abstracts and posters presented at medical meetings.
Australis Cancer Therapy

In addition, toxicology testing was conducted, and clinical gap analysis was completed.
2019-01-01

2019-01-01

2025

Australis Cancer Therapy

Awarded FDA Orphan Drug Designation for malignant glioma and Rare Pediatric Disease Designation for pediatric-type diffuse high-grade glioma.
Australis Cancer Therapy

Scalable manufacturing.
Australis Cancer Therapy

GLP Toxicology and GMP manufacturing initiated.
Australis Cancer Therapy

FDA Pre-IND meeting.
Australis Cancer Therapy

Ready for first in human study (anticipated by year end).
2019-01-01
2019-01-01

What’s next?

With AUS_001 planned for clinical trials by the end of 2025, we’re excited to get AUS_001 to the people who need it.

But we can’t do it alone. We need your investment to take the next step in developing and delivering the groundbreaking AUS_001.

What’s next?

With AUS_001 planned for clinical trials by the end of 2025, we’re excited to get AUS_001 to the people who need it.

But we can’t do it alone. We need your investment to take the next step in developing and delivering the groundbreaking AUS_001.

Join us on this important journey to find new therapies for patients with cancer

We are seeking investors and partners to join us in this mission. For more information, details on ongoing studies, and next steps, please reach out to us.